Vitiligo and substances that should be avoided

Anyone suffering from Vitiligo (or any other skin depigmentation) should avoid any substance that could cause or worsen depigmentation including the following:

Benzoyl peroxide: Benzoyl peroxide is a topical acne product which exhibits antibacterial activity. This is how it works: it presents antimicrobial effects against Propionibacterium acnes, which is the predominant organism in sebaceous follicles and comedones. The main mechanism of action of benzoyl peroxide depends on the release of oxygen free-radicals, which are capable of oxidizing bacterial proteins. However, this same mechanism can also damage melanocytes in people with skin depigmentation.

Hydroquinone: this is a product that inhibits melanogenesis. It may achieve this by inhibiting one or more steps in the tyrosine-tyrosinase pathway of melanin synthesis. As a results it causes skin depigmentation. Arbutine is a glucoside of hydroquinone and is hydrolysed to hydroquinone. Both products cause skin depigmentation.

Hydrogen peroxide: commonly used to disinfect the skin and for the cleaning of wounds.

Trichloroacetic acid, Phenolic acid, Glicolic acid, Fruit acids and, in general, creams and lotions used for peelings.

Retinoic acid and its by-products used in certain topical preparations.

Shampoos and cosmetics used to clear skin complexion.

Substances used for bleaching.

Any other chemical substance capable of irritating or damaging the skin should be carefully avoided.